Hormones & Metabolism

Depression, mood instability, or slowed thinking unresponsive to other treatments

Depression, mood instability, and mental fogginess that don't respond to antidepressants or standard psychiatric care often have a hidden cause: thyroid dysfunction. Most routine psychiatric evaluations skip the comprehensive thyroid testing needed to catch subtle imbalances - yet thyroid hormones are among the most neurologically active substances in the human body. At Renew Health & Wellness, Dr. Jennifer Redmond, CNP, DNP includes thorough thyroid evaluation as part of every visit involving mood, cognitive, or energy concerns.

Her thyroid panel includes:

  • TSH

  • Free T3

  • Free T4

  • Reverse T3

  • Thyroid antibodies

Hypothyroidism directly reduces the production and effectiveness of your brain's key neurotransmitters - dopamine, serotonin, and GABA. These are the chemicals that regulate your mood, motivation, and emotional resilience. When thyroid hormone levels are low, the result can look almost identical to major depression. This is why so many patients struggle for years on antidepressants without real relief. The root cause isn't a lack of medication - it's an underlying thyroid imbalance that has never been properly identified or treated.

Hashimoto's thyroiditis - an autoimmune condition where the immune system attacks the thyroid - is particularly linked to mood instability and depressive episodes. Some patients experience what is known as Hashimoto's encephalopathy, a condition where autoimmune inflammation affects the brain and nervous system, causing psychiatric and neurological symptoms. If Hashimoto's is driving your mood symptoms, Dr. Jennifer Redmond, CNP, DNP takes an integrative approach that goes beyond hormone therapy alone, targeting the autoimmune inflammation at its source.

For patients with autoimmune thyroiditis, Dr. Jennifer Redmond, CNP, DNP pairs thyroid hormone therapy with:

  • Anti-inflammatory nutritional strategies to calm immune activity

  • Selenium supplementation to lower thyroid antibody levels and reduce neurological inflammation

When Free T3 is optimized to a level that truly supports brain function, many patients experience dramatic improvements in mood, motivation, and mental clarity - results that antidepressants alone were never able to provide.

At Renew Health & Wellness, we treat both the biological and emotional dimensions of thyroid-related mood disorders. Our on-site mental health therapist works directly alongside Dr. Jennifer Redmond, CNP, DNP to provide integrated support - ensuring that every aspect of your experience receives expert attention. Your mental health deserves a thyroid evaluation.

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This content is for educational purposes only. Please book an appointment with Renew Health & Wellness to receive recommendations that are truly curated to you and your needs.

This content is for educational purposes only. Please book an appointment with Renew Health & Wellness to receive recommendations that are truly curated to you and your needs.

Contact

(605) 261-6872

info@renewhealthsd.com

2520 S. Lorraine Pl Sioux Falls, SD 57106

Copyright 2026 Renew Health and Wellness

Contact

(605) 261-6872

info@renewhealthsd.com

2520 S. Lorraine Pl Sioux Falls, SD 57106

Copyright 2026 Renew Health and Wellness

Contact

(605) 261-6872

info@renewhealthsd.com

2520 S. Lorraine Pl Sioux Falls, SD 57106

Copyright 2026 Renew Health and Wellness